Major Industry Experience
Head of Computational
Proteomics (2002-2003) at Myriad Proteomics, Inc. (later renamed to
"Prolexys Pharmaceuticals, Inc."), Salt Lake City, UT
- Created and managed a
bioinformatics department of 7 staffs (3 PhDs and 4 Masters) on an annual
budget of ~1.5million dollars.
- In less than 2 years, led the
group to create a terabyte-scale data processing and warehousing system to
help company perform knowledge discovery of ~80,000 human protein
interactions from 1.5 million yeast 2-hybrid search experiments.
- Led and executed successful
collaborations with companies such as Oracle, Spotfire, PubGene and
researchers at MIT Whitehead.
- Facilitated company's business
model change based on group's bioinformatics discovery of dozens of
promising drug candidates in colon cancer and neurodegenerative diseases.
Bioinformatics Computer
Scientist (1998-2002) Affymetrix, Inc., Santa Clara, CA
- First year as "senior
informatics consultant" for the bioinformatics department.
- Led sequence selections for
Affymetrix GeneChip products of human U95, mouse U74, and rat U34, which
generated multi-million dollar monthly revenue for the company.
- Influenced corporate IT upgrade
of Sun E6k to Sun E10k due to work in high-performance parallel computing.
- Conducted large-scale discovery
informatics research in high-throughput EST clustering, complex data model
design, datawarehouse design, SNP discovery, gene expression algorithm
development, etc.
Staff Supervised
I express my gratitude to the
following colleague scientists, engineers, and statisticians from my group, who
contributed to the success of various bioinformatics and computational
proteomics projects under my supervision at Myriad and have moved on to new exciting
opportunities thereafter:
Manjula Alimina
(bioinformatics consulting in the San Francisco Bay Area, 2003-), Andrey Sivachenko, Ph.D.(Ariadne Genomics, Inc.,
2004-), Hsiao-kun Tu (Medical
ProteoScope, Inc, 2004-), Mitsuhiro Kanazawa (Medical ProteoScope, Inc, 2004-),
Hisayoshi Zaima, Ph.D. (Hitachi Life
Science Group, 2003-), Amit Phansalkar (University of Utah, 2005-), and
Xianfeng (Jeff) Chen, Ph.D. (Virginia
Bioinformatics Institute, 2005-)